Pseudomonas protegens Pf-5, PFL_5439 (leuS)

Gene Feature Overview

Strain	Pseudomonas protegens Pf-5 GCF_000012265.1|latest
Locus Tag	PFL_5439
Name	leuS
Replicon	chromosome
Genomic location	6208893 - 6211499 (+ strand)

Cross-References

RefSeq	YP_262507.1
GI	70732744
EC Number	6.1.1.4
Entrez	3479831
INSDC	AAY94649.1
NCBI Locus Tag	PFL_5439
UniParc	UPI000054E012
UniProtKB Acc	Q4K5H6
UniProtKB ID	SYL_PSEF5
UniRef100	UniRef100_Q4K5H6
UniRef50	UniRef50_A8AJG0
UniRef90	UniRef90_Q4K5H6

Product

Feature Type	CDS
Coding Frame	1
Product Name	leucyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7)	-22.96
Kyte-Doolittle Hydrophobicity Value	-0.329
Molecular Weight (kDa)	96953.4
Isoelectric Point (pI)	5.20

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 668 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001694 (534 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PFL_5439 Search term: leuS Search term: leucyl-tRNA synthetase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000495707 leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095] E-value: 3.8e-164 Percent Identity: 37.7
Ensembl 110, assembly GRCh38.p14	ENSP00000495093 leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095] E-value: 3.8e-164 Percent Identity: 37.7
Ensembl 110, assembly GRCh38.p14	ENSP00000498867 leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095] E-value: 3.8e-164 Percent Identity: 37.7

References