Pseudomonas protegens Pf-5, PFL_6002 (hemC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas protegens Pf-5
GCF_000012265.1|latest
Locus Tag
PFL_6002
Name
hemC
Replicon chromosome
Genomic location 6822092 - 6823033 (- strand)

Cross-References

RefSeq YP_263060.1
GI 70733286
EC Number 2.5.1.61
Entrez 3480373
INSDC AAY95191.1
NCBI Locus Tag PFL_6002
UniParc UPI000054E22B
UniProtKB Acc Q4K3X3
UniProtKB ID HEM3_PSEF5
UniRef100 UniRef100_Q4K3X3
UniRef50 UniRef50_Q4K3X3
UniRef90 UniRef90_Q4K3X3

Product

Feature Type CDS
Coding Frame 1
Product Name
porphobilinogen deaminase
Synonyms
Evidence for Translation
Charge (pH 7) -9.70
Kyte-Doolittle Hydrophobicity Value 0.003
Molecular Weight (kDa) 33421.7
Isoelectric Point (pI) 4.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 586 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004841 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PFL_6002
Search term: hemC

Human Homologs

Ensembl 110, assembly GRCh38.p14
hydroxymethylbilane synthase [Source:HGNC Symbol;Acc:HGNC:4982]
E-value: 6.7e-63
Percent Identity: 42.6
Ensembl 110, assembly GRCh38.p14
hydroxymethylbilane synthase [Source:HGNC Symbol;Acc:HGNC:4982]
E-value: 6.7e-63
Percent Identity: 42.6
Ensembl 110, assembly GRCh38.p14
hydroxymethylbilane synthase [Source:HGNC Symbol;Acc:HGNC:4982]
E-value: 6.7e-63
Percent Identity: 42.6
Ensembl 110, assembly GRCh38.p14
hydroxymethylbilane synthase [Source:HGNC Symbol;Acc:HGNC:4982]
E-value: 6.7e-63
Percent Identity: 42.6

References

No references are associated with this feature.