Pseudomonas protegens CHA0, PFLCHA0_c00230 (def1)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas protegens CHA0 - Assembly GCF_000397205.1
GCF_000397205.1|latest |
| Locus Tag |
PFLCHA0_c00230
|
| Name |
def1
|
| Replicon | chromosome |
| Genomic location | 24339 - 24980 (- strand) |
Cross-References
| RefSeq | YP_007997334.1 |
| GI | 501677508 |
| EC Number | 3.5.1.88 |
| Entrez | 15557939 |
| NCBI Locus Tag | PFLCHA0_c00230 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
peptide deformylase Def
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 2.32 |
| Kyte-Doolittle Hydrophobicity Value | -0.427 |
| Molecular Weight (kDa) | 24566.1 |
| Isoelectric Point (pI) | 7.99 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 1IX1 | HYDROLASE | 06/07/02 | Crystal Structure of P.aeruginosa Peptide deformylase Complexed with Antibiotic Actinonin | Pseudomonas aeruginosa | 1.85 | X-RAY DIFFRACTION | 91.1 |
| 1S17 | HYDROLASE | 01/05/04 | Identification of Novel Potent Bicyclic Peptide Deformylase Inhibitors | Pseudomonas aeruginosa | 1.95 | X-RAY DIFFRACTION | 91.6 |
| 1N5N | HYDROLASE | 11/06/02 | Crystal Structure of Peptide Deformylase from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 1.8 | X-RAY DIFFRACTION | 91.6 |
| 1LRY | HYDROLASE | 05/16/02 | Crystal Structure of P. aeruginosa Peptide Deformylase Complexed with Antibiotic Actinonin | Pseudomonas aeruginosa | 2.6 | X-RAY DIFFRACTION | 91.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 587 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000019 (537 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PFLCHA0_c00230
Search term: def1
Search term: peptide deformylase Def
|
Human Homologs
References
No references are associated with this feature.