Pseudomonas protegens CHA0, PFLCHA0_c25960 (bkdA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas protegens CHA0 - Assembly GCF_000397205.1
GCF_000397205.1|latest
Locus Tag
PFLCHA0_c25960
Name
bkdA1
Replicon chromosome
Genomic location 2846286 - 2847344 (- strand)

Cross-References

RefSeq YP_007999871.1
GI 501680045
EC Number 1.2.4.4
Entrez 15560512
NCBI Locus Tag PFLCHA0_c25960

Product

Feature Type CDS
Coding Frame 1
Product Name
2-oxoisovalerate dehydrogenase subunit beta
Synonyms
Evidence for Translation
Charge (pH 7) -9.78
Kyte-Doolittle Hydrophobicity Value -0.103
Molecular Weight (kDa) 38.5
Isoelectric Point (pI) 5.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2BP7 OXIDOREDUCTASE 04/18/05 New crystal form of the Pseudomonas putida branched-chain dehydrogenase (E1) PSEUDOMONAS PUTIDA 2.9 X-RAY DIFFRACTION 91.2
1QS0 OXIDOREDUCTASE 06/24/99 Crystal Structure of Pseudomonas Putida 2-oxoisovalerate Dehydrogenase (Branched-Chain Alpha-Keto Acid Dehydrogenase, E1B) Pseudomonas putida 2.4 X-RAY DIFFRACTION 91.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 531 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002214 (793 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PFLCHA0_c25960
Search term: bkdA1

Human Homologs

Ensembl 110, assembly GRCh38.p14
branched chain keto acid dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:987]
E-value: 2.9e-78
Percent Identity: 46.2
Ensembl 110, assembly GRCh38.p14
branched chain keto acid dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:987]
E-value: 2.9e-78
Percent Identity: 46.2

References

No references are associated with this feature.