Pseudomonas poae RE_1-1-14, H045_06975 (metH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas poae RE*1-1-14
GCF_000336465.1|latest
Locus Tag
H045_06975
Name
metH
Replicon chromosome
Genomic location 1513643 - 1517353 (- strand)

Cross-References

RefSeq YP_007396963.1
GI 447916395
EC Number 2.1.1.13
Entrez 14503195
INSDC AGE25467.1
NCBI Locus Tag H045_06975
UniParc UPI0002AF47AB
UniProtKB Acc M4K1K0
UniProtKB ID M4K1K0_9PSED
UniRef100 UniRef100_M4K1K0
UniRef50 UniRef50_P13009
UniRef90 UniRef90_G8Q6L5

Product

Feature Type CDS
Coding Frame 1
Product Name
B12-dependent methionine synthase
Synonyms
Evidence for Translation
Charge (pH 7) -45.52
Kyte-Doolittle Hydrophobicity Value -0.159
Molecular Weight (kDa) 135401.4
Isoelectric Point (pI) 4.74

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 506 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003557 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: H045_06975
Search term: metH

Human Homologs

Ensembl 110, assembly GRCh38.p14
5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]
E-value: 0.0e+00
Percent Identity: 54.0
Ensembl 110, assembly GRCh38.p14
5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]
E-value: 0.0e+00
Percent Identity: 51.0
Ensembl 110, assembly GRCh38.p14
5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]
E-value: 0.0e+00
Percent Identity: 48.3
Ensembl 110, assembly GRCh38.p14
5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]
E-value: 0.0e+00
Percent Identity: 52.0
Ensembl 110, assembly GRCh38.p14
5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]
E-value: 0.0e+00
Percent Identity: 51.7
Ensembl 110, assembly GRCh38.p14
5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]
E-value: 0.0e+00
Percent Identity: 54.3

References

No references are associated with this feature.