Pseudomonas poae RE_1-1-14, H045_12070

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas poae RE*1-1-14
GCF_000336465.1|latest
Locus Tag
H045_12070
Name
Replicon chromosome
Genomic location 2787027 - 2788115 (+ strand)

Cross-References

RefSeq YP_007397975.1
GI 447917407
Entrez 14504207
INSDC AGE26479.1
NCBI Locus Tag H045_12070
UniParc UPI0002A7A2F2
UniProtKB Acc M4K0I2
UniProtKB ID M4K0I2_9PSED
UniRef100 UniRef100_M4K0I2
UniRef50 UniRef50_P10182
UniRef90 UniRef90_O68897

Product

Feature Type CDS
Coding Frame 1
Product Name
glutaminase-asparaginase
Synonyms
Evidence for Translation
Charge (pH 7) 0.97
Kyte-Doolittle Hydrophobicity Value -0.020
Molecular Weight (kDa) 38.8
Isoelectric Point (pI) 7.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
6-hydroxy-L-norleucine DB03412 DrugBank 5.1.4 P06608 L-asparaginase 43.2 359 2.9e-70
D-Aspartic Acid DB02655 DrugBank 5.1.4 P06608 L-asparaginase 43.2 359 2.9e-70
6-hydroxy-D-norleucine DB02233 DrugBank 5.1.4 P06608 L-asparaginase 43.2 359 2.9e-70

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 359 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001273 (453 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: H045_12070

Human Homologs

References

No references are associated with this feature.