Pseudomonas aeruginosa PACS2, A0K_RS08905

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa PACS2
GCF_000168335.1|latest
Locus Tag
A0K_RS08905
Name
Replicon chromosome
Genomic location 1866458 - 1867222 (- strand)

Cross-References

RefSeq ZP_01364562.1
GI 107100644
NCBI Locus Tag A0K_RS08905

Product

Feature Type CDS
Coding Frame 1
Product Name
N(G),N(G)-dimethylarginine dimethylaminohydrolase
Synonyms
Evidence for Translation
Charge (pH 7) -6.46
Kyte-Doolittle Hydrophobicity Value -0.229
Molecular Weight (kDa) 28.5
Isoelectric Point (pI) 5.42

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3BPB HYDROLASE 12/18/07 Crystal structure of the dimethylarginine dimethylaminohydrolase H162G adduct with S-methyl-L-thiocitrulline Pseudomonas aeruginosa 2.81 X-RAY DIFFRACTION 99.2
3RHY HYDROLASE 04/12/11 Crystal structure of the dimethylarginine dimethylaminohydrolase adduct with 4-chloro-2-hydroxymethylpyridine Pseudomonas aeruginosa 2.18 X-RAY DIFFRACTION 99.6
1H70 HYDROLASE 06/30/01 DDAH FROM PSEUDOMONAS AERUGINOSA. C249S MUTANT COMPLEXED WITH CITRULLINE PSEUDOMONAS AERUGINOSA 1.8 X-RAY DIFFRACTION 99.2

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001153 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: A0K_RS08905

Human Homologs

Ensembl 110, assembly GRCh38.p14
dimethylarginine dimethylaminohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:2715]
E-value: 1.8e-26
Percent Identity: 30.8

References

No references are associated with this feature.