Pseudomonas aeruginosa PACS2, A0K_RS11960

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa PACS2
GCF_000168335.1|latest
Locus Tag
A0K_RS11960
Name
Replicon chromosome
Genomic location 2506504 - 2507358 (- strand)

Cross-References

RefSeq ZP_01365145.1
GI 107101227
NCBI Locus Tag A0K_RS11960

Product

Feature Type CDS
Coding Frame 1
Product Name
methenyltetrahydrofolate cyclohydrolase
Synonyms
Evidence for Translation
Charge (pH 7) -4.96
Kyte-Doolittle Hydrophobicity Value 0.053
Molecular Weight (kDa) 30.5
Isoelectric Point (pI) 6.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4A5O OXIDOREDUCTASE 10/26/11 Crystal structure of Pseudomonas aeruginosa N5, N10- methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD) PSEUDOMONAS AERUGINOSA PAO1 2.2 X-RAY DIFFRACTION 99.6

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003602 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: A0K_RS11960

Human Homologs

Ensembl 110, assembly GRCh38.p14
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434]
E-value: 1.6e-58
Percent Identity: 43.7
Ensembl 110, assembly GRCh38.p14
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434]
E-value: 1.6e-58
Percent Identity: 43.7
Ensembl 110, assembly GRCh38.p14
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like [Source:HGNC Symbol;Acc:HGNC:31865]
E-value: 1.6e-58
Percent Identity: 43.7
Ensembl 110, assembly GRCh38.p14
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like [Source:HGNC Symbol;Acc:HGNC:31865]
E-value: 1.6e-58
Percent Identity: 43.7

References

No references are associated with this feature.