Pseudomonas aeruginosa PACS2, A0K_RS18960

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa PACS2
GCF_000168335.1|latest
Locus Tag
A0K_RS18960
Name
Replicon chromosome
Genomic location 4039496 - 4040515 (- strand)

Cross-References

RefSeq ZP_01366444.1
GI 107102526
NCBI Locus Tag A0K_RS18960

Product

Feature Type CDS
Coding Frame 1
Product Name
UDP-N-acetylenolpyruvoylglucosamine reductase
Synonyms
Evidence for Translation
Charge (pH 7) -2.90
Kyte-Doolittle Hydrophobicity Value -0.233
Molecular Weight (kDa) 37.5
Isoelectric Point (pI) 6.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7ORZ OXIDOREDUCTASE 06/06/21 Crystal structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Pseudomonas aeruginosa in complex with FAD and a pyrazole derivative (fragment 18) Pseudomonas aeruginosa PAO1 1.85 X-RAY DIFFRACTION 99.1
4JB1 OXIDOREDUCTASE 02/19/13 Crystal structure of P. aeruginosa MurB in complex with NADP+ Pseudomonas aeruginosa 2.1 X-RAY DIFFRACTION 99.1
4JAY OXIDOREDUCTASE 02/19/13 Crystal structure of P. aeruginosa MurB in complex with NADP+ Pseudomonas aeruginosa 2.23 X-RAY DIFFRACTION 99.1
7OR2 OXIDOREDUCTASE 06/04/21 Crystal structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Pseudomonas aeruginosa in complex with FAD and a pyrazole derivative (fragment 4) Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.35 X-RAY DIFFRACTION 99.1
7OSQ OXIDOREDUCTASE 06/09/21 Crystal structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Pseudomonas aeruginosa in complex with FAD and a pyrazole derivative (fragment 18) Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.07 X-RAY DIFFRACTION 99.1

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002605 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: A0K_RS18960

Human Homologs

References

No references are associated with this feature.