Pseudomonas aeruginosa PAO1, PA5304 (dadA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006091 generation of precursor metabolites and energy
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006807 nitrogen compound metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0008718 D-amino-acid dehydrogenase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 21378189 Reviewed by curator
Biological Process GO:0006558 L-phenylalanine metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004795 threonine synthase activity
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0019478 D-amino acid catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01202
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008718 D-amino-acid dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01202
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01266
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00360 Phenylalanine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-6422 D-arginine degradation 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Phenylalanine metabolism ECO:0000037
not_recorded
PseudoCAP Nitrogen metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF54373 FAD-linked reductases, C-terminal domain - - 270 360 1.11E-17
Hamap MF_01202 D-amino acid dehydrogenase [dadA]. IPR023080 D-amino acid dehydrogenase DadA 1 411 50.179291
Gene3D G3DSA:3.30.9.10 - - - 134 363 3.7E-52
MobiDBLite mobidb-lite consensus disorder prediction - - 410 424 -
SUPERFAMILY SSF51905 FAD/NAD(P)-binding domain IPR036188 FAD/NAD(P)-binding domain superfamily 1 416 2.07E-54
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 102 405 3.7E-52
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 1 71 2.5E-9
PANTHER PTHR13847 SARCOSINE DEHYDROGENASE-RELATED - - 2 419 4.6E-53
FunFam G3DSA:3.50.50.60:FF:000020 D-amino acid dehydrogenase - - 3 62 2.9E-34
MobiDBLite mobidb-lite consensus disorder prediction - - 410 432 -
Pfam PF01266 FAD dependent oxidoreductase IPR006076 FAD dependent oxidoreductase 3 398 1.7E-71

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.