Pseudomonas poae RE_1-1-14, H045_18045

Gene Feature Overview

Strain	Pseudomonas poae RE*1-1-14 GCF_000336465.1|latest
Locus Tag	H045_18045
Name
Replicon	chromosome
Genomic location	4118157 - 4122356 (- strand)

Cross-References

RefSeq	YP_007399167.1
GI	447918599
EC Number	2.7.7.6
Entrez	14505399
INSDC	AGE27671.1
NCBI Locus Tag	H045_18045
UniParc	UPI0002A7A234
UniProtKB Acc	M4K560
UniProtKB ID	M4K560_9PSED
UniRef100	UniRef100_M4K560
UniRef50	UniRef50_A7ZUK2
UniRef90	UniRef90_Q4K527

Product

Feature Type	CDS
Coding Frame	1
Product Name	DNA-directed RNA polymerase subunit beta'
Synonyms
Evidence for Translation
Charge (pH 7)	2.50
Kyte-Doolittle Hydrophobicity Value	-0.210
Molecular Weight (kDa)	154.7
Isoelectric Point (pI)	7.21

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
7XL4	TRANSCRIPTION	04/21/22	Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (closed lobe)	Pseudomonas aeruginosa PAO1	3.86	ELECTRON MICROSCOPY	92.4
7XYB	TRANSCRIPTION	06/01/22	The cryo-EM structure of an AlpA-loaded complex	Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT	3.7	ELECTRON MICROSCOPY	92.4
7XYA	TRANSCRIPTION	06/01/22	The cryo-EM structure of an AlpA-loading complex	Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT	3.3	ELECTRON MICROSCOPY	92.4
7XL3	TRANSCRIPTION	04/21/22	Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (open lobe)	Pseudomonas aeruginosa PAO1	3.13	ELECTRON MICROSCOPY	92.4
7F0R	TRANSCRIPTION/DNA	06/06/21	Cryo-EM structure of Pseudomonas aeruginosa SutA transcription activation complex	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT	5.8	ELECTRON MICROSCOPY	92.4
7VF9	TRANSCRIPTION	09/10/21	Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes	Pseudomonas aeruginosa PAO1	4.04	ELECTRON MICROSCOPY	92.4

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 667 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001442 (533 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: H045_18045 Search term: DNA-directed RNA polymerase subunit beta'

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000502190 RNA polymerase II subunit A [Source:HGNC Symbol;Acc:HGNC:9187] E-value: 1.9e-56 Percent Identity: 22.4
Ensembl 110, assembly GRCh38.p14	ENSP00000494840 RNA polymerase II subunit A [Source:HGNC Symbol;Acc:HGNC:9187] E-value: 1.9e-56 Percent Identity: 22.4

References